Learn how you can benefit today from the NutraBlast Vitamins B12
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What is Vitamins B12?
Vitamin B-12 is a water-soluble vitamin, like all other B-vitamins. This means it can dissolve in water and travel through the bloodstream. The human body can store vitamin B-12 for up to four years. Any excess or unwanted vitamin B-12 is excreted in the urine. Vitamin B-12 is the largest and most structurally complicated vitamin. It occurs naturally in meat products and can only be industrially produced through bacterial fermentation synthesis.
The History of Vitamins B12
In the 1850s the English physician Thomas Addison described a lethal (pernicious) form of anaemia that could be related to pathological gastric mucosa and associated with the absence of acid in the stomach. Georges Richard Minot, an MD from Harvard, had the idea that something in food might help patients. In 1923 Minot teamed up with William Parry Murphy basing their investigations on previous work by George Whipple at Johns Hopkins. Whipple had bled dogs to make them anaemic and then determined which foods restored red blood cells. Red meat and some vegetables were effective, but liver was best of all. In 1926, at a meeting in Atlantic City, Minot and Murphy reported the sensational finding that 45 patients with pernicious anaemia had been cured by ingestion of large quantities of raw liver and that “clinical improvement had been obvious, usually within 2 weeks” There was much scepticism at the time but for their research Minot, Murphy, and Whipple received the Nobel Prize for Medicine in 1934. On 12 December 1934 Murphy delivered his Nobel lecture and in the concluding paragraph stated “Rather than enlarge further upon the details and results of the treatment of pernicious anemia, I shall now present, with your permission, a motion picture which will illustrate many points more clearly than I could discuss them here.” What is probably the motion picture that he was referring to was re-discovered and can be viewed here. It shows the remarkable recovery of the patients after treatment with liver. Some of the typical symptoms of PA can be seen, fatigue, weight loss, unsteady gait. These days we would expect to diagnose the B12 deficient patient before the disease had progressed to the stages shown, still, it is a salutary reminder that neurological symptoms are an important facet of B12 deficiency. Still however, the active ingredient in liver was not known. An ‘Intrinsic Factor’ is also involved Three years later William Castle also at Harvard, discovered that something in the stomach must be related to the disease as people with removal of the stomach often died of pernicious anaemia, liver did not work as a cure. He postulated an “intrinsic factor”, present in the gastric mucosa, was necessary for normal absorption of the “extrinsic factor” in the liver. The “intrinsic factor” was lacking in pernicious anaemia patients. In 1948 the “extrinsic factor” was isolated in crystalline form from liver and published (within weeks of each other) by Karl Folkers and his co-workers at Merck, and E Lester-Smith and his group at Glaxo, and named vitamin B12. In 1956, the British chemist, Dorothy Hodgkin, described the structure of this large molecule, for which she received the Nobel Prize for Chemistry in 1964. In 1971 the organic chemist Robert Woodward (himself a Nobel laureate in 1965) announced the successful synthesis of the vitamin after ten years of effort. A disease that had been fatal could now easily be treated by injections of pure vitamin B12, and without side effects. The patients recovered completely. Vitamin B12 deficiency was firmly linked with the concept of anaemia. However the haematological symptoms in vitamin B12 deficiency were accompanied by many other symptoms (as described by Addison) particularly neurologic or neuropsychiatric changes. These symptoms were long believed to be secondary to the anaemia. The prevailing idea maintained that no vitamin B12 deficiency occurred without anaemia. Recently, It has become evident that anaemia is just one of many symptoms of B12deficiency, and that symptoms can frequently not be accompanied by anaemia at all. The prevalence of vitamin B12 deficiency is more common than previously estimated. True pernicious anaemia with a lack of intrinsic factor, constitutes only a small fraction of all cases. Far more common may be malabsorption due to atrophic gastritis arising from decreased secretion of gastric acid and enzymes required for the cleavage of protein-bound vitamin B12 from food. The diagnostic challenge concerns those patients that are vitamin B12 deficient, and who would benefit from treatment, who have no clear signs or symptoms or obvious anaemia. It is difficult to diagnose these patients but important to do so since the treatment is readily administered, safe and effective and neurological impairment may be irreversible if treatment is initiated too late. Active B12, which appears to be an early marker of B12 depletion, could provide a solution.
The Top 4 Reasons You Need Vitamins B12
The most commonly cited lecithin benefits include:
1. Helps Maintain Energy Levels Vitamin B12 benefits your metabolism because it’s needed to convert carbohydrates into useable glucose in the body. Glucose from carbohydrate foods is used as a form of energy, so this is the reason why people with vitamin B12 deficiencies often experience fatigue. Vitamin B12 is also needed for neurotransmitter signaling that helps your muscles contract and gives you energy to go about your day without feeling tired and run down.
2. Prevents Memory Loss and Lowers Risk of Neurodegenerative Disease A vitamin B12 deficiency may cause various neurologic and psychiatric disturbances. Because of its role in nerve health and neurotransmitter signaling, vitamin B12 benefits cognitive function and is used to lower the risk of neurodegenerative diseases, including Alzheimer’s disease and dementia. (9) (10)
3. Boosts Mood and Helps the Nervous System to Properly Function One of the most researched vitamin B12 benefits is its ability to help in healthy regulation of the nervous system, including reducing such mood disorders as depression and anxiety. Vitamin B12, along with folate, is needed as a major determinant of one-carbon metabolism, which produces the compound called SAM (S-adenosyl methionine). SAM is crucial for neurological function, dealing with stress and mood regulation. (11) (12) Vitamin B12 is needed for concentration and cognitive processes, such as learning, so a vitamin B12 deficiency can result in difficulty focusing and an increased risk for attention disorders.
4. Plays a Role in Maintaining Heart Health Vitamin B12 benefits cardiovascular health in several ways, which is important considering the fact that heart disease is currently the number one cause of death worldwide. Vitamin B12 helps to reduce elevated homocysteine levels, which is now considered a major risk factor for heart disease. (13) Homocysteine is an amino acid and its levels in the blood are influenced by blood levels of B-complex vitamins, including vitamin B12. Vitamin B12 helps to protect against heart disease like a heart attack or stroke by lowering high homocysteine levels in the blood. There is also some evidence that B12 can help control high cholesterol and high blood pressure levels. B vitamins are also able to control atherosclerotic diseases, in which someone experiences a dangerous build-up of plaque in the arteries. (14)
Shocking Facts About Vitamins B12
Facts about Vitamin B12 Safety The facts about Vitamin B12 Supplements bear out that it is INCREDIBLY safe, even at high dosages. While doctors will regularly give 'standard' doses of 0.5 to 1 mg, studies have used Vitamin B12 Deficiency Treatment dosages up to 40 mg per day (that's 40,000 micrograms) with no problems, no overdoses, and practically zero Side Effects, except in those with the MTHFR Gene Mutation who are taking cyanocobalamin when they should be taking Methylcobalamin. It just seems to be an extremely safe nutritional supplement to use on a regular basis. 2. It's Not from Plants or Animals Probably one of the most interesting facts about Vitamin B12 is that it is not made from plants and it's not made from animals. It's actually made from MICROORGANISMS! This is why plants do not contain Vitamin B12 (unless they are 'contaminated' with soil) and that is why animal products DO have vitamin B12- they ARE contaminated with microorganisms. This is one of the reasons that having Good Bacteria in the bowels is so important; the human body actually can make it's own Vitamin B12! This is also one of the great Benefits of Sauerkraut and other lactofermented foods- they contain B12 because of the good bacteria present. Even chlorella- which are algae and considered to be a source of B12 for vegans- gets its Vitamin B12 from a symbiotic relationship with bacteria! 3. It Helps to Relieve Fatigue One of the most we'll known facts about vitamin B12 is that it helps to relieve fatigue. While it SHOULD only work in those who are deficient, there are MANY people who claim to get more energy with B12, particularly with Vitamin B12 Injections. This is likely because the Vitamin B12 Levels are so inaccurate that those who feel better taking vitamin b12 are really vitamin b12 deficient- but have just gone undiagnosed. In any case, Vitamin B12 Shot Problems DO occur, and shots are COMPLETELY UNNECESSARY even in even those who BELIEVE they need shots or who their doctors tell them that they MUST have shots. Yes, I said that Vitamin B12 Shots are unnecessary for EVERYONE. This is because B12 is now made to be taken sublingually under the tongue which gets the vitamin directly into your bloodstream- just like shots. If you think that you need shots or even KNOW that you ONLY respond to shots, it's likely they you really just need to take a higher dosage than the 'standard' 0.5 to 1 mg dosage. Try experimenting with dosages up to 10 mg per day, as volunteers did in one study, and you'll likely find that you don't need to keep spending all that extra money on shots when Vitamin B12 Supplements will do the same job. 4. It's Powers of Detoxification Are Astounding The facts about Vitamin B12 show that it is an amazingly powerful detoxifying agent, particularly when it's used in the form ofMethylcobalamin B12. Its power lies in the 'Methyl' part of the Methylcobalamin as a process known as 'Methylation' is probably one of the most critical processes in the body. Unfortunately, a large percentage of the population has a gene known as the MTHR gene that appears to make it more difficult to perform this process leading to a variety of potential diseases that may be related to difficulty with methylation such as breast cancer, autism and other diseases. Vitamin B12 has been individually studied in the detoxification of MANY different substances including: • Arsenic • Mercury • Glutamates from artificial sweeteners and MSG • Mycotoxins • Cyanide The Vitamin B12 Facts show that it is amazingly effective at helping the body's methylation processes get rid of these foreign substances.
Why Vitamins B12 Is The #1
The most controversial vitamin out among them all, quite possibly, vitamin B12 is something everyone must have and must have enough of in order to be healthy. This one vitamin keeps our blood, nervous system, and heart-healthy — it even helps make DNA — the genetic makeup of our bodies. It fuels our brain, metabolism, and even affects our digestion and how we absorb food. You might also be aware that it prevents a type of anemia that can cause fatigue and overall low energy. It’s common knowledge that vitamin B12 is found in animal-based foods, primarily meat, eggs, and dairy. However, eating too much animal protein can cause significant inflammatory health problems in the body, not to mention long-term effects of an animal protein-heavy diet prove that we need another answer for our diets in helping ensure long-term health. It’s estimated that somewhere between 1.5 percent to 15 percent of the general American population is vitamin B12 deficient, and your chances of being deficient only increase as you age. Vitamin B12 deficiency symptoms can include depression, confusion, poor memory, balance problems, tingling and numbness in the hands and feet, and more. (1) If you suffer from any of these issues, you may need more vitamin B12 foods in your diet. What is vitamin B12? Vitamin B12, also called cobalamin, is a water-soluble vitamin that’s essential to red blood cell production, healthy brain and nerve function, as well DNA synthesis. Even a mild vitamin B12 deficiency can result in impaired mental function and low energy. Vitamin B12 also plays a role in the formation of red blood cells, so a deficiency can lead to the production of large, immature cells that are unable to properly carry oxygen.
Top 3 Questions People Ask About Vitamins B12
There are a few frequently asked questions about these Vitamins B12.
1. What foods might naturally contain B12? Animal foods, including meat, milk, and eggs, contain B12 and are essentially the exclusive source of the vitamin in the American food supply (not counting supplements or fortification). Two varieties of edible algae (Dried green (Enteromorpha sp.) and purple (Porphyra sp.) seaweed (nori)) have been found to have active B12, but other algae have inactive B12-analog compounds that have no apparent benefit in animal metabolism. Some varieties of mushrooms and some foods made with certain fermentation processes have very small amounts of active B12.
2. . How do animals get B12? They absorb B12 made by their gut bacteria, in the case of ruminants like cows and sheep. They eat poop (coprophagia), like some rodents do. (Please don’t get any bright ideas from this fact!) They have bacterial contamination of their food. They eat animal-sourced foods like other animal flesh, milk, or eggs.
3. Who is at risk for B12 deficiency? Adults over the age of 50 who have atrophic gastritis (their stomach isn’t making as much acid) may not absorb B12 as well. This accounts for the majority of deficiency in older adults. Because atrophic gastritis may be relatively common, a B12 supplement or fortified foods are recommended by the Institute of Medicine for all adults over age 50, regardless of diet.
Tips for a Vitamins B12
As Dr. Williams mentioned, vitamin B12 is crucial to keeping the brain healthy, and it’s also critical to the health of just about every cell and system, including the blood and nervous system. The liver stores it for us, so even when we don’t get it every day, we usually aren’t at risk of deficiency for awhile. The trick with vitamin B12, however, is absorption. The stomach has to secrete enough acid plus the digestive enzyme “pepsin” to extract vitamin B12 from food. Once it’s free, the nutrient has to combine with a protein known as “intrinsic factor” secreted by the stomach lining, which protects it while it’s transported to the small intestine for absorption. That means we have to have a healthy stomach and a well-functioning pancreas (which produces the digestive enzymes) in order to properly absorb vitamin B12.